Based upon extensive research with law enforcement, gangs, inmates, migrants, and addicts, all walks of life intersect in this fentanyl exposé. With potency one hundred times that of heroin and nearly undetectable at the border, fentanyl has flooded the market, triggering a tidal wave of overdoses, crime, and addiction. Work hits too close to home for Tulsa drug cop, Layne West (Dale), when his son, Jack (Jones), becomes an addict. In conjunction with his partner, Ty (Carroll), and FBI counterpart, Beatty (Cochrane), West makes it his mission to take down those responsible, including the Mexican cartel’s local shot-caller, Ramón Garza (Mando), Indian Brotherhood War Chief, Holt Lightfeather (Greene), who controls state-wide trafficking from inside the Oklahoma State Penitentiary at McAlester a.k.a. “Big Mac,” and the local Irish Mob family outfit, led by George “Smiley” Greene (Foster), along with his mother, Ginger (Leo), and uncle, Mickey (Coster). As Holt educates West: “The cartels want your kids, the next generation, who want what is new, and fentanyl is new.”